Pill of the Month

October 2008-Guaifenesin and Codeine

Guaifenesin and Codeine
Brand Name: Robitussin AC

Uses:
Temporarily controls cough due to minor throat and bronchial irritation as may occur with the common cold or inhaled irritants. Helps loosen phlegm and thin bronchial secretions to make coughs more productive.

Mechanisms:
This syrup preparation combines the expectorant, guaifenesin, with the cough suppressant, codeine. Guaifenesin enhances the output of lower respiratory tract fluid. The enhanced flow of less viscid secretions promotes and facilitates the removal of mucus. Codeine is a centrally acting agent which elevates the threshold for cough. As a result, dry, unproductive coughs become more productive and less frequent.

Side Effects:
Side effects include severe dizziness or drowsiness, confusion, hallucinations, unusual thoughts or behavior, urinating less than usual or not at all, slow heart rate, weak pulse, fainting, weak or shallow breathing, dizziness, drowsiness, headache.


References: http://www.drugs.com/ and www.rxlist.com