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Pill of the Month
September 2009-Oxycodone HCl (Oxycontin)
Oxycodone
HCl
Brand Names: Oxycontin
Uses:
Oxycontin,
tablets are an opioid analgesic supplied in 10 mg, 20 mg, 40 mg, 80 mg,
and 160 mg tablet strengths for oral administration. The
tablet strengths describe the amount of oxycodone per tablet as the
hydrochloride salt. OxyContin Tablets are a controlled-release oral
formulation of oxycodone hydrochloride indicated for the
management of moderate to severe pain when a continuous, around-the
clock analgesic is needed for an extended period of time. It is to be
administered every 12 hours. Oxycontin is a strong narcotic
pain-reliever and cough suppressant that is related to
morphine, codeine and hydrocodone.
Drug Mechanism:
The
precise mechanism of action is not known but may involve stimulation of
opioid receptors in the brain. Oxycodone does not eliminate the
sensation of pain but decreases discomfort by increasing tolerance to
pain. In addition to tolerance to pain, oxycodone also causes sedation
and respiratory depression
Side Effects:
Adverse
events such as constipation should be anticipated, which could be
treated with a stimulant laxative. Other opioid-related side effects
such as sedation and nausea are usually self-limited and
often do not persist beyond the first few days. It is also addictive so
use only when prescribed.
Reference: www.rxlist.com/oxycontin-drug.htm
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